What is the use of Coenzyme Q10? Do you want to add?
Coenzyme Q10 is a coenzyme of mitochondrial enzyme complex, which plays an important role in cell energy production. Currently, it is mostly used as an auxiliary drug in clinic.
How does Coenzyme Q10 work?
Coenzyme Q10 (CoQ10) is a naturally occurring compound in the human body that can be synthesized in the body and ingested externally.
In the human body, Coenzyme Q10 derived from tyrosine or phenylalanine to synthesize benzoquinone structure and from acetyl Coenzyme A (CoA) to synthesize polyisoprene side chain via the valerate pathway, and then further modified and condensed to form Coenzyme Q10 by hydroxylation, methylation and decarboxylation.
External intake mainly comes from meat, offal (such as liver), oily fish (such as salmon and tuna), whole grains, nuts, etc., and is also an important source of coQ10 in the human body.
The heart is the organ that requires and consumes the most energy in the body. Myocardial metabolism and energy supply disorders involved in the pathological processes of various cardiovascular diseases.
When coQ10 is deficient, the heart, an organ with high energy requirements, is greatly affected.
The possible mechanism of action of coenzyme Q10 is:
- Participate in oxidative phosphorylation by regulating electron transfer in the electron transport chain;
- Antioxidant or free radical scavenger can maintain the morphological structure of mitochondria of ischemic cardiomyocytes, reduce peripheral vascular resistance, and increase cardiac output.
- Raising the threshold of ventricular arrhythmia and antiarrhythmic;
- Antagonizing aldosterone then inhibits myocardial remodeling.
The role of Coenzyme Q10?
(1) Promote energy production
95% of the body’s energy production is related to coQ10.
As an important coenzyme in the body, it involved in a series of complex reactions that help cells convert carbohydrates obtained from food into an important energy molecule, adenosine triphosphate (ATP).
Coenzyme Q10 can make people energetic, physical strength and endurance can be improved, no longer feel tired, is the first choice for athletes to enhance and quickly recover physical strength.
(2) Antioxidant
Coenzyme Q10 has a powerful antioxidant effect, clearing free radicals, keeping cells from damage and protecting cell health, and its antioxidant capacity is 50 times that of vitamin E.
In addition to its own antioxidant effects, Coenzyme Q10 can also strengthen and regenerate other antioxidants, such as vitamin E, ascorbic acid, lipoic acid and so on.
Vitamin E can prevent the spread of the chain reaction in the process of lipid peroxidation by cleaning up lipid peroxidation free radicals, and coenzyme Q10 can reduce the α-tocopheryl free radicals produced by vitamin E when cleaning free radicals, thus saving and regenerating vitamin E.
(3) Enhance immunity
Coenzyme Q10 can enhance the ability of the immune system, the immune system is the best natural barrier against various diseases, protecting the heart, liver, kidney and other important organs from bacteria and viruses.
Studies have found that the concentration of CoQ10 in patients with breast cancer, prostate cancer, pancreatic cancer and colon cancer is lower than that of normal people, suggesting that coenzyme Q10 as a non-specific immune enhancer can play a good role in improving the body’s immunity, anti-inflammation and anti-tumor.
In addition, the study also found that CoQ10 has a certain positive effect on viral myocarditis, viral hepatitis, chronic hepatitis, diabetic neuritis, chronic obstructive pneumonia, bronchitis, asthma, periodontitis, etc., and can reduce the adverse reactions caused by radiotherapy and chemotherapy in cancer patients.
(4) Improve heart health
The heart is a high energy consuming organ, and its coenzyme Q10 content is the highest in all organs of the human body, and it is also the most sensitive to CoQ10.
The human body lacks coQ10, and the heart is usually the first to affected. Almost all evidence suggests that CoQ10 improves cardiac muscle function and improves heart health.
It has reported that coenzyme Q10 can increase the survival of heart failure by 300%, and more than 75% of patients with heart disease improve significantly after taking Coenzyme Q10, greatly reducing the risk of sudden death.
In addition to these benefits, CoQ10 has shown to protect the brain and nerve cells, prevent neurodegenerative diseases (stroke, Parkinson’s disease, and Alzheimer’s disease), lower blood pressure, reduce the pain and frequency of migraines, rapidly improve gum health, and neutralize the side effects of statins.
